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Biotechnology
Below are the latest entries in the Biotechnology channel.
We have 94 results for Biotechnology.
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Thursday 20th of November 2008 07:33:49 AM
they found that treating mice with Imatinib or a similar inhibitor drug for seven weeks before the onset of auto-immune (type 1) diabetes prevented development of the disease long after the treatment was stopped.
Only 20 per cent of the animals treated with Imatinib became progressively diabetic by 30 weeks of age, as opposed to 71 per cent of those who did not have the drug.
The majority of imatinib-treated mice remained non-diabetic at 50 weeks of age, suggesting that the short-term therapy had long-term effects on the development of diabetes.
The drug put 80 per cent of mice with existing disease into remission when mice were treated for eight to 10 weeks after disease onset.
These findings suggest that the cancer drug could be used to treat type 1 diabetes and, possibly, other auto-immune diseases. However, trials are needed to confirm whether the drug confers the same effect on humans. See full article.
Related Entries:
Anticancer Drug Against Hodgkin's and Leukemia Granted Orphan Drug Status - 31 January 2006
FTY720 May Treat Imatinib (Gleevec)- Resistant Leukemia - 28 August 2007
Gleevec®, Proven Safe and Effective Over The Long Term - 13 November 2007
Cancer Drug Gleevec May Treat Type 1 Diabetes - 19 November 2008
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From biotech-weblog.com Research This Blog Entry
Monday 17th of November 2008 05:42:02 PM
In a pilot study, the olive stones were pre-treated using high-pressure hot water before the addition of enzymes which degrade plant matter and generate sugars. The hydrolysate obtained from this process was then fermented with yeasts to yield about 5.7 kg of ethanol per 100kg of olive stones. See full article.
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Compound May Boost Biofuel Production from Plant Fiber - 09 November 2006
T. reesei Genome Analysis Reveals Potential in Biofuel Production - 07 May 2008
Sweet Potato as Biofuel Source - 28 August 2008
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From biotech-weblog.com Research This Blog Entry
Sunday 16th of November 2008 09:55:33 AM
They tested TAT2 in several ways. First, they exposed the CD8 T-cells from HIV-infected persons to TAT2 to see if the chemical not only slowed the shortening of the telomeres but improved the cells' production of soluble factors called chemokines and cytokines, which had previously been shown to inhibit HIV replication. It did. They then took blood samples from HIV-infected individuals and separated out the CD8 T-cells and the CD4 T-cells - those infected with HIV. They treated the CD8 T-cells with TAT2 and combined them with the CD4 T-cells in the dish and found that the treated CD8 cells inhibited production of HIV by the CD4 cells.Researchers say that given these properties, the compound may be useful not only in treating HIV disease, but also immunodeficiency and increased susceptibility to other viral infections associated with chronic diseases or aging. The study See full article.
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From biotech-weblog.com Research This Blog Entry
Sunday 16th of November 2008 04:14:37 AM
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From biotech-weblog.com Research This Blog Entry
Friday 31st of October 2008 09:55:58 AM
In the study, published in the International Journal of Obesity, Friedman and lead author Hong Ji, PhD, screened rats for vulnerability to diet-induced obesity by measuring the increase in blood triglyceride levels following a single high-fat meal. They then fed the rats a diet high in fat over the next four weeks.
The researchers were able to predict which animals would become obese over the four-week period by examining the earlier metabolic response to the high-fat meal: the smaller the triglyceride change, the greater the weight gain.
The researchers hopes to determine whether such a blood test is also an effective predictor of future weight gain in humans. See full article.
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Top Biotech Hubs for 2007 - 26 February 2007
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Tuesday 28th of October 2008 11:47:15 AM
Ronald and her colleagues used the new rice microarray to investigate gene expression changes when plants are grown in the light versus the dark. They then combined this gene expression data with biochemical pathway data to correctly predict the function of genes whose role was previously unknown. The newly identified genes carry out light-related biochemical processes such as photosynthesis and photorespiration.The rice oligonucleotide near-whole genome array, called the rice NSF45K array, is publicly available here. S ee full article.
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Rice Genome Fully Sequenced - 19 August 2005
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Genetically Engineered Flood-Tolerant Rice - 11 August 2006
GIF1 Gene: Key To High-Yield Rice - 29 September 2008
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From biotech-weblog.com Research This Blog Entry
Monday 27th of October 2008 10:35:39 AM
See news release from the John Innes Center and the study published in Nature Biotechnology, doi:10.1038/nbt.1506.
Note: Two years ago, I reported on the work of a group of scientists from Oregon State University also working on purple tomatoes. See full article.
Related Entries:
Animal Model to Test Allergenic Potential of Genetically Engineered Crops - 06 October 2006
Genetically Modified Eggplants Goes on Field Trials - 09 October 2007
BtCorn Toxins May Harm Stream Ecosystems - 11 October 2007
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From biotech-weblog.com Research This Blog Entry
Sunday 26th of October 2008 09:20:23 AM
"In our fundus we have three substances - myxopyronin, corallopyronin and ripostatin - which were isolated and characterised chemically and biologically. Already many years ago we recognized their unusual antibiotic effect. It was directed in an unknown manner against the bacterial RNA polymerase, i.e. the enzyme that reads the DNA of the pathogen. In eukaryontic cells, which human cells are also belonging to, the substances do not attack the RNA polymerase."
The results supported the indication that the natural substances block the bacterial RNA polymerase in a new manner: the natural substances append to another location within the RNA polymerase than the antibiotics previously investigated.
They attach to the enzyme - which looks like an open crab claw - directly at its joint position. Subsequently the enzyme is no longer able to open the claw. By this mechanism of action the active substances prevent the RNA polymerase from adhering to the DNA - reading of the genetic materials is suppressed completely. This new mechanism also operates in bacteria that are resistant to conventional antibiotics.
The study has been published in the journal Cell, doi 10.1016/j.cell.2008.09.033.
Source See full article.
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Green Tea Increases Antibiotic Efficacy - 31 March 2008
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From biotech-weblog.com Research This Blog Entry
Tuesday 21st of October 2008 08:44:55 AM
"In laboratory-scale studies, the data show that orange peel has a considerable potential for the removal of dyes from aqueous solutions over a wide range of concentrations," Benaïssa says. "Orange peel may be used as a low-cost, natural and abundant source for the removal of dyes, and it may be an alternative to more costly materials. It may also be effective in removing other harmful or undesirable species present in the waste effluents."
Their findings have been published in the International Journal of Environment and Pollution.
See full article.
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From biotech-weblog.com Research This Blog Entry
Monday 20th of October 2008 09:36:10 AM
The researchers disrupted communication between the bacteria and the hosts in two ways: raising normal mice under germ-free conditions so they lacked the bacteria, and genetically engineering other mice to lack Gpr41 so they were unable to respond to the bacteria.
In both cases, the mice weighed less and had a leaner build than their normal counterparts even though they all ate the same amount.
The researchers also found that in mice without Gpr41, the intestines passed food more quickly. They hypothesized that one action of Gpr41 is to slow down the motion that propels food forward, so that more nutrients can be absorbed. Thus, if the receptor cannot be activated, food is expelled more quickly, and the animal gets less energy from it.
The researchers suggest that the Gpr41 receptor may be a likely target for drugs that can fight a certain kind of obesity by slowing down the absorption of energy from the gut. See full article.
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Two Protein Receptors Control Stomach Relaxation Identified - 05 March 2008
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From biotech-weblog.com Research This Blog Entry
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